Quinolines and derivatives

Medchemexpress LLC Canagliflozin | 842133-18-0 | MFCD18251436 | 99.7% | 444.52 | C24H25FO5S | 200 MG

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Canagliflozin is a selective sodium-glucose cotransporter 2 (SGLT2) inhibitor provided as a research-grade powder for biochemical and pharmacological studies. It exhibits low-nanomolar potency against SGLT2 and is used in in vitro and in vivo experiments to investigate glucose transport and metabolic pathways.

• Selective SGLT2 inhibitor with low-nanomolar IC50 values.
• High purity suitable for analytical and research use (≈99.7% LCMS).
• Solid powder form for flexible formulation and dosing.
• Stable under recommended storage conditions (powder: -20°C and 4°C).
• Molecular weight 444.52 and formula C24H25FO5S.

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Medchemexpress LLC Fasiglifam (TAK-875) | 1000413-72-8 | MFCD18251445 | 99.0% | 524.63 | C29H32O7S | 200 MG

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Fasiglifam (TAK-875) is a potent, selective, orally bioavailable GPR40 (FFAR1) agonist used in research to study glucose-dependent insulin secretion and GPR40 pharmacology. The compound is supplied as a solid research reagent with documented potency and chemical characterization (formula C29H32O7S; MW 524.63 g/mol).

• Potent, selective GPR40 agonist with reported EC50 of 72 nM.
• Orally bioavailable pharmacology profile suitable for in vitro and in vivo studies.
• High purity (~99%) suitable for laboratory research.
• Available in multiple sizes including milligram and gram quantities.
• Chemical formula C29H32O7S and molecular weight 524.63 g/mol.

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Medchemexpress LLC Ro 31-9790 | 145337-55-9 | 99.4% | 315.41 g/mol | C15H29N3O4 | 1 ML

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Ro 31-9790 is a synthetic metalloproteinase (MMP) inhibitor used in biochemical and cell-based research. It blocks L-selectin shedding and modulates cytokine shedding in immune cells, displaying submicromolar to micromolar potency across different cell types. The compound is provided as a concentrated solution for laboratory assays and requires appropriate storage and handling.

• Inhibits L-selectin and TNF-α shedding in immune cells.
• Potent activity with IC50 values as low as 0.3 μM.
• Supplied as a 10 mM solution in DMSO for ready-to-use dosing.
• High purity suitable for research applications.
• High DMSO solubility (50 mg/mL) with warming or sonication if needed.
• Stable in solvent when stored at -80°C for long-term preservation.

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eMolecules​ 92921-24-9 | Sulfo-N-succinimidyl 4-(maleimidomethyl)cyclohexane-1-carboxylate sodium salt | Chem-Impex | MFCD00054978 | 436.370 | C16H17N2NaO9S | 96.000 | [Na+].[O-]S(=O)(=O)C1CC(=O)N(OC(=O)C2CCC(CN3C(=O)C=CC3=O)CC2)C1=O | 50mg | 272386939

Sulfo-N-succinimidyl 4-(maleimidomethyl)cyclohexane-1-carboxylate sodium salt | Chem-Impex | 92921-24-9 | MFCD00054978 | 436.370 | C16H17N2NaO9S | 96.000 | [Na+].[O-]S(=O)(=O)C1CC(=O)N(OC(=O)C2CCC(CN3C(=O)C=CC3=O)CC2)C1=O | 50mg | 272386939

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eMolecules​ 66575-29-9 | Forskolin | Target Molecule | MFCD00082317 | 410.507 | C22H34O7 | 0.000 | CC(=O)O[C@H]1[C@@H](O)[C@H]2C(C)(C)CC[C@H](O)[C@]2(C)[C@@]2(O)C(=O)C[C@@](C)(O[C@]12C)C=C | 200mg | 376015962

Forskolin | Target Molecule | 66575-29-9 | MFCD00082317 | 410.507 | C22H34O7 | 0.000 | CC(=O)O[C@H]1[C@@H](O)[C@H]2C(C)(C)CC[C@H](O)[C@]2(C)[C@@]2(O)C(=O)C[C@@](C)(O[C@]12C)C=C | 200mg | 376015962

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eMolecules​ 68181-17-9 | SPDP | Target Molecule | MFCD00009636 | 312.360 | C12H12N2O4S2 | 0.000 | O=C(CCSSc1ccccn1)ON1C(=O)CCC1=O | 200mg | 348530991

SPDP | Target Molecule | 68181-17-9 | MFCD00009636 | 312.360 | C12H12N2O4S2 | 0.000 | O=C(CCSSc1ccccn1)ON1C(=O)CCC1=O | 200mg | 348530991

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eMolecules​ 957486-82-7 | Azido-PEG6-amine | ChemScene | MFCD03453240 | 350.416 | C14H30N4O6 | 97.000 | NCCOCCOCCOCCOCCOCCOCCN=[N+]=[N-] | 250mg | 672544878

Azido-PEG6-amine | ChemScene | 957486-82-7 | MFCD03453240 | 350.416 | C14H30N4O6 | 97.000 | NCCOCCOCCOCCOCCOCCOCCN=[N+]=[N-] | 250mg | 672544878

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eMolecules​ 103476-89-7 | Leupeptin Hemisulfate | Target Molecule951.200 | C40H78N12O12S | 0.000 | OS(O)(=O)=O.CC(C)C[C@H](NC(C)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCN=C(N)N)C=O.CC(C)C[C@H](NC(C)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCN=C(N)N)C=O | 25mg | 448758926

Leupeptin Hemisulfate | Target Molecule | 103476-89-7951.200 | C40H78N12O12S | 0.000 | OS(O)(=O)=O.CC(C)C[C@H](NC(C)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCN=C(N)N)C=O.CC(C)C[C@H](NC(C)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCN=C(N)N)C=O | 25mg | 448758926

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eMolecules​ 1255942-06-3 | DBCO-amine | ChemScene | MFCD22380759 | 276.339 | C18H16N2O | 95.000 | NCCC(=O)N1Cc2ccccc2C#Cc2ccccc12 | 50mg | 686111611

DBCO-amine | ChemScene | 1255942-06-3 | MFCD22380759 | 276.339 | C18H16N2O | 95.000 | NCCC(=O)N1Cc2ccccc2C#Cc2ccccc12 | 50mg | 686111611

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eMolecules​ 7681-84-7 | Tetrahydrofuran-2-carbaldehyde, 50% in toluene | Combi-Blocks | MFCD01726184 | 100.117 | C5H8O2 | 90.000 | O=CC1CCCO1 | 250mg | 517119334

Tetrahydrofuran-2-carbaldehyde, 50% in toluene | Combi-Blocks | 7681-84-7 | MFCD01726184 | 100.117 | C5H8O2 | 90.000 | O=CC1CCCO1 | 250mg | 517119334

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eMolecules​ 21635-88-1 | oxetan-3-amine | Pharmablock | MFCD08544363 | 73.095 | C3H7NO | 97.000 | NC1COC1 | 50mg | 551053873

oxetan-3-amine | Pharmablock | 21635-88-1 | MFCD08544363 | 73.095 | C3H7NO | 97.000 | NC1COC1 | 50mg | 551053873

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eMolecules​ OXETAN-3-AMINE 25MG

5000192488 OXETAN-3-AMINE 25MG

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eMolecules​ 4965-36-0 | 7-Bromoquinoline | Key Organics/BIONET | MFCD03695823 | 208.058 | C9H6BrN | 95.000 | Brc1ccc2cccnc2c1 | 1mg | 564169976

7-Bromoquinoline | Key Organics/BIONET | 4965-36-0 | MFCD03695823 | 208.058 | C9H6BrN | 95.000 | Brc1ccc2cccnc2c1 | 1mg | 564169976

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Medchemexpress LLC Sulfo-LC-SPDP (sodium) | 169751-10-4 | MFCD00083162 | >90.0% | 527.57 | C18H22N3NaO8S3 | 25 MG

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Sulfo-LC-SPDP (sodium) is a water-soluble, cleavable heterobifunctional crosslinker that introduces a reducible disulfide linkage between amine and sulfhydryl groups. It is used as an ADC linker and for protein conjugation in research.

• Water-soluble, cleavable heterobifunctional linker.
• Introduces a reducible disulfide bond for controlled payload release.
• Contains an NHS ester for reaction with primary amines.
• Contains a pyridyldithiol group for reaction with thiols.
• Provided as the sodium salt for improved aqueous solubility.
• Available in small-mass quantities suitable for research-scale conjugation.

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Medchemexpress LLC Mal-amido-PEG10-C2-NHS ester | 1137109-22-8 | MFCD20226950 | 777.81 g/mol | C34H55N3O17 | 250 MG

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Mal-amido-PEG10-C2-NHS ester is a PEG-based, non-cleavable linker containing a maleimide group and an N-hydroxysuccinimide (NHS) ester. The NHS ester enables conjugation to primary amines on proteins, amine-modified oligonucleotides, and other amine-containing molecules, while the maleimide allows thiol-selective coupling. This reagent is supplied for research use only.

• Non-cleavable PEG-based linker with maleimide and NHS ester functionality.
• Enables amine and thiol bioconjugation for protein and oligonucleotide labeling.
• Molecular weight approximately 777.8 g/mol for predictable mass additions.
• Provided as a small-molecule reagent suitable for research applications.
• Store in a tightly closed container in a cool, dry, well-ventilated place.

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